Acne (5e Disease)
From D&D Wiki
This disease causes the afflicted's skin to turn red and form pockets of pus every 1d12 minutes. The effects worsen after 2d4 days as pus now erupts from your skin every 1d8 minutes, causing you to fail all Charisma skill checks for 1d4 hours after the eruption. The only cure is the oil of the mystic Tea Tree which is only cultivated by the most experienced of alchemists.