Quadrimurfractiphobia (3.5e Flaw)
From D&D Wiki
You are terrified of the fourth wall being broken.
Effect: Whenever you or anyone else says something not immediately related to the game you are playing, you must make a DC 15 Will save to avoid falling prone and cowering until somebody other than yourself finds a way for whatever is said to be incorporated into the game (no matter how ridiculous or arbitrary). You must cower for at least one full round.
Roleplaying Ideas: You had just cast Magic Missile into the darkness, when someone in the other room asks where the Cheetos are. You fail your will save and therefore fall and cower until the DM says that it was a kobold whose snack you just blasted who said it, rather than someone in the other room.