Potions and Poisons (Demon Slayer Supplement)

Wisteria Poison

Poison, Rare

This violet-hued toxin, distilled from the sacred Wisteria flower, is deadly to demonic creatures. When applied to a weapon (lasts 1 minute or until a successful hit), it affects only demons.
Wisteria Weakness. A Demon struck by a weapon coated in this poison must make a DC 15 Constitution saving throw. On a failed save, the demon takes 6d6 poison damage and is paralyzed for 1 minute. On a success, the creature takes half damage and suffers no additional effects. An affected creature can attempt the saving throw again at the end of its turns.

Weak Dose. Non-demons are unaffected. A Demon who succeeds on three saving throws against this poison becomes immune to that batch for 24 hours.

Can also be released as a 10-foot-radius gas cloud, requiring all demons in the area to make the same save.

Shinobu's Compound Poison

Poison, Very Rare

A custom mixture crafted by the Insect Hashira, Shinobu Kocho, this poison combines wisteria and other compounds to overcome demon regeneration.
Powerful Concoction. A Demon struck by this poison must make a DC 17 Constitution saving throw. On a failed save, the target takes 6d6 poison damage, cannot regenerate hit points for 1 minute, and has disadvantage on attack rolls and ability checks for 1 minute. On a successful save, it takes half damage and no other effects.

If a creature is slain by this poison, its body decays rapidly and can only be revived by a Wish spell or similar divine intervention.

Anti-Muzan Drug

Poison, Legendary

This four-stage compound, created by Tamayo, is a legendary poison designed to destroy the progenitor of demons.
Careful Application. Must be administered over four rounds (or via massive dose) into a Demon. Administering the poison makes the creature undergo a DC 18 Constitution saving throw. On a failure, the poison takes effect, and proceeds to the next stage on the beginning of the creature's turns:

• Humanization Attempt. DC 18 Constitution save. On failure, the target loses access to legendary actions and lair actions for 1 minute.
• Cellular Degeneration. Target takes 8d6 necrotic damage. Regeneration is disabled.
• Aging Acceleration. Target gains 1 level of exhaustion per round for 3 rounds.
• Cellular Collapse. Target takes 50 force damage. If reduced to 0 HP, the target is obliterated and cannot be resurrected except by a Wish spell.

Only affects demons. Works once per creature; if resisted, that demon becomes permanently immune.

Humanization Potion

Potion, Legendary

This rare serum was developed by Tamayo to revert demons to their human form.
Humanization. A Demon that drinks this potion must make a DC 20 Constitution saving throw. On a failed save, the creature permanently reverts to a human and loses all demonic abilities. On a successful save, nothing happens.

Only works on demons with some remaining humanity or emotion.

Shinobu's Insect Venoms

Poison, Uncommon

A concentrated venom derived from wisteria and tailored to Shinobu's weaponry.
Venom. On a successful weapon hit, a Demon must make a DC 14 Constitution saving throw. On a failure, it takes 3d6 poison damage and has disadvantage on Constitution saves for 1 minute.

Multiple Mixes.

• Sleep Venom. On a second failed save, the creature falls unconscious for 1 minute.
• **Pain Venom. Target has disadvantage on melee attacks for 1 minute.

Applies to one slashing or piercing weapon for 1 minute.

Demon Slayer's Healing Ointment

Potion, Common

An herbal remedy used by the Demon Slayer Corps for emergency treatment.
Ointment. Restores 2d4 + 2 hit points and removes the Bleeding or poisoned condition. Also grants advantage on the next saving throw against exhaustion or poison made within the next hour.

Breathing Enhancer Inhalant

Potion, Rare

An herbal vapor compound used to enhance a Slayer's breathing form under pressure.
Boost. For 1 minute, the user has advantage on Constitution saving throws and deals +2 damage with weapon and Breath-style attacks.

After the effect ends, the user must make a DC 12 Constitution saving throw or gain 1 level of exhaustion. Each use beyond the first in a 24-hour period increases the DC by 5.

Demon Blood Art Suppressant

Poison, Very Rare

A rare compound designed to prevent demons from accessing their supernatural blood arts.
Suppressant. A demon hit by this poison or exposed to it via inhalation must make a DC 16 Constitution saving throw. On a failed save, the creature cannot use any spell-like or supernatural abilities for 1 minute. If it attempts to do so, it takes 2d6 psychic damage per attempt.

No effect on non-demons.

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